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BAY 73-1449
CAS No. 693790-96-4
BAY 73-1449 ( BAY73-1449; BAY 73-1449 )
Catalog No. M27855 CAS No. 693790-96-4
BAY 73-1449 is a selective and potent antagonist of the prostacyclin receptor(IC50<0.1 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 222 | Get Quote |
|
| 10MG | 372 | Get Quote |
|
| 25MG | 623 | Get Quote |
|
| 50MG | 887 | Get Quote |
|
| 100MG | 1197 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBAY 73-1449
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NoteResearch use only, not for human use.
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Brief DescriptionBAY 73-1449 is a selective and potent antagonist of the prostacyclin receptor(IC50<0.1 nM).
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DescriptionBAY 73-1449 is a selective and potent antagonist of the prostacyclin receptor(IC50<0.1 nM).(In Vivo):In male Wistar rats, BAY 73-1449 (0.1-1 mg/kg; i.v.) significantly reduced splenic shunt vessel outflow without affecting mesenteric inflow. BAY 73-1449 (1-5 mg/kg; s.c.) has no effects on portal pressures and the degree of porto-systemic shunting in rats.
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SynonymsBAY73-1449; BAY 73-1449
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PathwayOthers
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TargetOther Targets
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RecptorRhoA; Lbc
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Research Area——
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Indication——
Chemical Information
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CAS Number693790-96-4
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Formula Weight425.5
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Molecular FormulaC26H23N3O3
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Purity>98% (HPLC)
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Solubility——
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SMILESOC(=O)[C@H](Cc1ccccc1)Nc1cc(ncn1)-c1ccc(OCc2ccccc2)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Francesca FANELLI, et al. Compounds and composition for use in the inhibition of the lbc-rhoa interaction, in particular for the treatment of cancer. WO2015028929A1.
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