BAY 73-1449

CAS No. 693790-96-4

BAY 73-1449 ( BAY73-1449; BAY 73-1449 )

Catalog No. M27855 CAS No. 693790-96-4

BAY 73-1449 is a selective and potent antagonist of the prostacyclin receptor(IC50<0.1 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 222 Get Quote
10MG 372 Get Quote
25MG 623 Get Quote
50MG 887 Get Quote
100MG 1197 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    BAY 73-1449
  • Note
    Research use only, not for human use.
  • Brief Description
    BAY 73-1449 is a selective and potent antagonist of the prostacyclin receptor(IC50<0.1 nM).
  • Description
    BAY 73-1449 is a selective and potent antagonist of the prostacyclin receptor(IC50<0.1 nM).(In Vivo):In male Wistar rats, BAY 73-1449 (0.1-1 mg/kg; i.v.) significantly reduced splenic shunt vessel outflow without affecting mesenteric inflow. BAY 73-1449 (1-5 mg/kg; s.c.) has no effects on portal pressures and the degree of porto-systemic shunting in rats.
  • Synonyms
    BAY73-1449; BAY 73-1449
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    RhoA; Lbc
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    693790-96-4
  • Formula Weight
    425.5
  • Molecular Formula
    C26H23N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC(=O)[C@H](Cc1ccccc1)Nc1cc(ncn1)-c1ccc(OCc2ccccc2)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Francesca FANELLI, et al. Compounds and composition for use in the inhibition of the lbc-rhoa interaction, in particular for the treatment of cancer. WO2015028929A1.
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